Anhydrous Piperazine
Anhydrous Piperazine

Anhydrous Piperazine

Anhydrous Piperazine (CAS 110850), supplied by Shandong Xima, is a hygroscopic cyclic diamine with ≥99.0 % industrialgrade purity. As a key organic synthesis buildingblock, it serves pharmaceutical, polymercuring and gaspurification workflows with strictlycontrolled impurity profiles for bulk global buyers.
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cas 110-85-0

Product Overview

 

Anhydrous Piperazine, abbreviated as PIP, has CAS No.110-85-0 and molecular formula C₄H₁₀N₂. It falls under the amides & amines subclass of organic chemicals. Under ambient conditions, it appears as white deliquescent flakes or crystalline solid with a pungent amine-like odour. This cyclic secondary diamine exhibits strong hygroscopicity and readily absorbs moisture from ambient air. It dissolves freely in water and ethanol, forming strongly alkaline aqueous solutions, while reacting vigorously with strong acids, acid halides and oxidising agents. Thanks to its two reactive secondary-amine sites on the six-membered heterocyclic ring, it can undergo sequential substitution reactions to produce various piperazine-derivative intermediates widely used across multiple industrial sectors.

 

Full Product Description

 

Industrial-grade Anhydrous Piperazine from Shandong Xima Supply Chain is a trusted cyclic-diamine feedstock for pharmaceutical-intermediate manufacturers, epoxy-curing-agent producers and gas-treatment facilities worldwide. Its core characteristic stems from the dual reactive secondary-amine functional groups located on its saturated heterocyclic framework. Unlike linear aliphatic diamines, its rigid cyclic molecular structure brings unique steric-hindrance effects, enabling selective N-substitution reactions under controlled reaction conditions. This structural feature helps generate target heterocyclic derivatives and reduces undesired cross-linking side-products during multi-step synthetic routes. Operators must bear in mind its pronounced hygroscopic property; prolonged exposure to humid surroundings causes moisture uptake, which lowers product assay and disturbs subsequent reaction stoichiometry.

A key advantage of our anhydrous piperazine lies in tight restrictions on critical trace impurities including water content, related amine homologues and heavy-metal residues. Excess moisture or foreign amine contaminants will shift reaction molar ratios and decrease yields during piperazine-derivative synthesis for pharma or polymer-material production. Our qualified industrial-grade material holds these undesirable trace components within narrow technical thresholds, which are validated via gas-chromatography and Karl-Fischer moisture testing. Besides its high solubility in polar protic solvents facilitates homogeneous feed mixing inside reactor vessels, removing complex pre-drying pre-treatment steps for properly-handled plant-scale synthetic operations.

Buyers gain tangible operational and commercial benefits by selecting our dependable anhydrous-piperazine supply. Well-controlled impurity and moisture specifications stabilise synthetic-reaction conversion rates and cut downstream-purification workload, lowering raw-material losses and production-related costs on client-side manufacturing lines. Our flexible bulk-inventory capacity accommodates both long-term framework contracts and urgent spot-order requirements for fine-chemical and gas-treatment manufacturers. Customers can sustain uninterrupted manufacturing cycles without frequent supplier changes. Every shipment comes with complete official documentation to streamline import-customs clearance and internal quality-audit workflows for overseas industrial enterprises.

These performance claims are backed by our rigorous supply-chain-control protocols. Each incoming batch of anhydrous piperazine undergoes representative sampling and in-house laboratory inspection prior to dispatch. Test metrics cover GC-determined assay purity, visual appearance, Karl-Fischer water content, amine-homologue impurities and heavy-metal levels. All measured results are documented in each lot's Certificate of Analysis. Our anhydrous piperazine has been exported for pharmaceutical-intermediate synthesis, epoxy-curing-agent and gas-sweetening projects, earning repeat orders from industrial end-users. We only source material from audited upstream manufacturers holding valid hazardous-chemical production permits to guarantee consistent raw-material quality.

Global chemical purchasers commonly express concerns regarding purity drift, excessive moisture absorption, amine-related impurities, incomplete hazard-related documentation and inconsistent delivery timelines for hygroscopic reactive cyclic-amine intermediates. As a licensed hazardous-chemical supply-chain trader, Shandong Xima conducts thorough pre-shipment inspections for every anhydrous-piperazine consignment. We maintain adequate safety stock for mainstream industrial-grade specifications to address urgent procurement requests. A full documentation package containing GHS-compliant MSDS, batch-specific COA, commercial invoice and packing list is prepared for customs-compliance purposes. Our technical-support team can provide practical guidance covering hermetic moisture-proof storage, low-humidity material-transfer protocols and personal-protection best practices to assist on-site plant operators in safely managing this hygroscopic cyclic-diamine compound.

 

CTA (Call-to-Action)

 

If you are sourcing qualified industrial-grade Anhydrous Piperazine for heterocyclic-intermediate synthesis, epoxy curing-agent preparation or industrial gas-sweetening applications, please do not hesitate to contact us. We support bulk wholesale, sample requests and consultations for custom-specification requirements. Request your latest quotation and full specification sheet today.

whatsapp:+8617356006695 Email:xima777@ximachem.com

 

FAQ

 

Q1: What grades and purity levels of Anhydrous Piperazine can you supply?

A: We mainly supply industrialgrade Anhydrous Piperazine with minimum purity ≥99.0 %. A COA reporting GC assay, KarlFischer water content, amineimpurity and heavymetal indexes is provided for every batch. Reach out to us if you have special technicalindex requirements.

Q2: What are the primary application fields for Anhydrous Piperazine?

A: It functions as a vital cyclicdiamine buildingblock for pharmaceutical heterocyclic intermediates, epoxy resin curing agents, gassweetening absorbents, and finechemical derivative synthesis workflows.

Q3: Can I obtain an Anhydrous Piperazine sample before placing a bulk order?

A: Sample services are available. Please send your sample specifications and delivery address via WhatsApp or email; our team will evaluate your request and propose a feasible sample solution. Hermetic moistureproof packaging is mandatory for this highly hygroscopic substance during transit.

Q4: What shipping documents can you provide for importcustoms clearance?

A: We provide GHSstandard MSDS, Certificate of Analysis (COA), commercial invoice and packing list for every shipment. Notify us in advance if you require additional certification documents.

Q5: What is your standard packaging for Anhydrous Piperazine?

A: Our standard packaging adopts hermetic moistureproof steel drums. We can discuss alternative packaging options subject to hazardousgoods transportation and storage regulations in destination countries.
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