Diethylformamide
Diethylformamide

Diethylformamide

N,N-Diethylformamide (DEF, CAS 617-84-5) is a clear, colorless to pale yellow liquid with a faint amine-like odor. It belongs to the class of tertiary amides, where the formyl group is bonded to a diethylamino group. As a polar aprotic solvent, DEF exhibits a high dielectric constant (ε = 36.7) and a wide liquid range (boiling point 175–177°C, freezing point < -70°C). Its unique properties—lower hygroscopicity than DMF (dimethylformamide) and better thermal stability than DMAC (dimethylacetamide)—make it a preferred solvent in moisture-sensitive reactions and high-temperature processes.
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Ethanol CAS NO.617-84-5

Product attributes

 

Our N,N-Diethylformamide is synthesized via the reaction of diethylamine with methyl formate or by carbonylation of diethylamine. It is then purified by fractional distillation under reduced nitrogen atmosphere to achieve high purity. Key specifications include:

Product Name

N,N-Diethylformamide

Also Known As

DEF/Diethylformamide/Formyldiethylamine

CAS No.

617-84-5

Molecular Formula

C₅H₁₁NO

Molecular Weight

101.15 g/mol

EINECS No.

210-533-2

Purity (GC)

≥99.0% / ≥99.5% / ≥99.9%

Grade

Industrial Grade / High Purity Grade / Electronic Grade

Water Content

≤0.1%-0.5%

Density (25℃)

0.900-0.908 g/mL

Boiling Point

176-178°C

Melting Point

-78°C

Flash Point

60-69°C

Refractive Index

n20/D 1.434

Vapor Pressure

1.04 mmHg

Packing

190kg/200kg net steel drum (lined), IBC (1000kg), ISO TANK, 25kg plastic drum, 500ml/1L/25L glass/HDPE bottle (lab grade)

UN No.

1993

Packing Group

III

 

Product Description

Features

Our N,N-Diethylformamide (DEF) is produced under strict quality control standards to ensure high purity, low moisture content, and stable chemical performance. It has excellent thermal stability and strong solvency, making it suitable for demanding high-temperature and high-pressure chemical reactions.

Advantages

Compared with standard industrial solvents, our DEF offers superior purity and reduced impurity content, ensuring more stable reaction conditions. Its balanced polarity and high boiling point provide better control in synthesis processes, reducing side reactions and improving overall reaction efficiency.

Benefits

Using high-quality DEF helps manufacturers improve reaction yield, enhance product purity, and optimize process efficiency. It supports more stable chemical synthesis environments, reduces production variability, and helps lower operational costs in pharmaceutical and fine chemical manufacturing.

Evidence

Laboratory analysis confirms DEF purity ≥99%, with strict control of water content and trace impurities. Our production follows ISO-compliant quality management systems, ensuring consistent performance and reliability for global industrial applications in synthesis and processing.

 

Application Examples

Pharmaceutical Industry

Solvent for API synthesis and intermediates

01

Organic Synthesis

Reaction medium for complex chemical reactions

02

Fine Chemicals

Intermediate and processing solvent

03

Polymer Industry

Used in specialty polymer production processes

04

Chemical Research

Laboratory-grade reaction solvent

05

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Call to Action

Looking for a reliable N,N-Diethylformamide CAS NO.617-84-5 supplier for pharmaceutical, industrial, or specialty chemical applications? Contact Shandong Xima Supply Chain Management Co., Ltd. today to receive customized specifications, competitive pricing,free COA sample, and dependable global supply solutions.

FAQ

 

Q1: What is N,N-Diethylformamide mainly used for?

A: It is mainly used as a polar aprotic solvent in pharmaceutical synthesis, organic reactions, and fine chemical production.

Q2: What is the purity of your DEF?

A: Our DEF typically has a purity of ≥99% with strict quality control.

Q3: Why is DEF used in organic synthesis?

A: Due to its high polarity, high boiling point, and strong solvency, it provides stable reaction conditions for complex synthesis.

Q4: What safety precautions are required for handling DEF?

A: DEF is a combustible liquid (flash point 65°C) and can cause skin/eye irritation. It may be absorbed through skin. Use chemicalresistant gloves (nitrile or neoprene), safety goggles, and adequate ventilation. Avoid open flames. Consult MSDS for detailed handling.

Q5: How should DEF be stored?

A: Store in a cool, dry, wellventilated area below 40°C, away from oxidizers and strong acids. Keep containers tightly sealed to prevent moisture ingress and volatile loss. Shelf life: 24 months under recommended conditions.

Q6: What is the recommended packaging for DEF?

A: We offer 190kg net steel drums, 1000L IBC totes, and bulk ISO tank containers. All packaging is designed for hazardous goods (UN 2734, Class 3, PG III).

Q7: What is the minimum order quantity (MOQ) for DEF?

A: One 190kg drum for trial. For regular commercial orders, MOQ is 3 drums (570kg) or one IBC tote. Bulk tank orders (18–20 metric tons) are available for large consumers.

Q8: What export documents do you provide for DEF shipments?

A: Commercial invoice, packing list, Bill of Lading, COA, MSDS, DG declaration, and upon request: Certificate of Origin (C/O), REACH compliance documentation, and GHS labels.

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