Ethanol CAS 865-48-5
Product Overview
Sodium tert-Butoxide (CAS No. 865-48-5) is a strong, non-nucleophilic organic base commonly supplied as a white to off-white powder or solution. It is produced by reacting tert-butanol with sodium metal or sodium derivatives and is widely utilized as a catalyst, condensation agent, and dehydrohalogenation reagent in organic synthesis. As one of the most important chemical intermediates in modern chemical manufacturing, Sodium tert-Butoxide plays a critical role in the production of pharmaceutical intermediates, agrochemical intermediates, fine chemicals, and specialty chemicals.
Product Description

In today's highly competitive chemical manufacturing industry, reaction efficiency, product purity, and process reliability directly influence production costs and final product quality. Sodium tert-Butoxide has become one of the preferred chemical intermediates for manufacturers worldwide because of its exceptional basicity, excellent selectivity, and broad application range in organic synthesis.
As a strong organic base, Sodium tert-Butoxide is particularly valuable in reactions where conventional inorganic bases may generate undesirable side reactions. Its bulky tert-butyl structure provides excellent steric hindrance, allowing chemists to achieve more selective reaction pathways while minimizing unwanted by-products. This characteristic makes it especially useful in the synthesis of pharmaceutical intermediates and specialty chemicals where product purity is a critical requirement.
One of the major features of Sodium tert-Butoxide is its outstanding catalytic efficiency. In various condensation, alkylation, cyclization, and elimination reactions, it helps accelerate reaction rates while improving overall conversion efficiency. For manufacturers, this translates into shorter production cycles, lower energy consumption, and increased productivity. These operational advantages make Sodium tert-Butoxide a highly cost-effective raw material for large-scale industrial applications.
The pharmaceutical industry relies heavily on high-performance reagents to ensure consistent product quality. Sodium tert-Butoxide is frequently employed in the synthesis of active pharmaceutical ingredients (APIs) and pharmaceutical intermediates because of its ability to promote highly selective transformations. Its controlled reactivity helps manufacturers achieve better yields while maintaining strict quality standards required by global pharmaceutical markets.
Beyond pharmaceuticals, Sodium tert-Butoxide is widely utilized in agrochemical production, polymer chemistry, and advanced material manufacturing. As a versatile specialty chemical reagent, it supports the synthesis of complex molecular structures required for modern industrial applications. Its compatibility with various organic solvents further expands its usefulness across multiple production environments.
From a quality assurance perspective, consistency is essential. Industrial users require every batch to perform identically to avoid process deviations and costly downtime. High-quality Sodium tert-Butoxide is manufactured under strict production controls to ensure stable purity, low impurity levels, and predictable performance characteristics. These quality standards are particularly important for customers involved in fine chemicals and high-value specialty chemical production.
Supply reliability is another important factor for global buyers. At Xima Chemical, we understand that uninterrupted supply is critical to maintaining production schedules. Supported by a mature chemical supply chain system, professional warehousing capabilities, and international logistics resources, we provide stable sourcing solutions for customers worldwide. Comprehensive technical documentation, including COA, SDS, and export certificates, is available to support regulatory compliance and procurement requirements.
For companies seeking a reliable strong base for demanding synthesis processes, Sodium tert-Butoxide offers an excellent combination of reactivity, selectivity, consistency, and commercial value. Its proven performance in pharmaceutical intermediates, chemical intermediates, fine chemicals, and specialty chemicals manufacturing continues to make it one of the most trusted reagents in industrial organic synthesis.
Why Choose Xima Chemical?
Features
High-purity Sodium tert-Butoxide
Strong non-nucleophilic organic base
Excellent catalytic activity
Consistent batch quality
Suitable for demanding synthesis reactions
.
Advantages
Improves reaction selectivity
Enhances product yield
Reduces by-product formation
Supports efficient large-scale production
Compatible with various industrial processes
Benefits
Lower manufacturing costs
Improved production efficiency
More stable product quality
Reduced process risks
Reliable long-term supply support
Evidence
Strict quality control procedures
Professional chemical export experience
Global supply capability
Comprehensive technical support documentation
Widely applied in pharmaceutical and fine chemical manufacturing industries

Call to Action
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- Competitive factory pricing
- Latest product specifications
- COA and SDS documentation
- Packaging recommendations
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Send your inquiry now and discover how our Sodium tert-Butoxide can help improve your manufacturing efficiency and product quality.
FAQ
Q: 1. What is Sodium tert-Butoxide used for?
A: Sodium tert-Butoxide is mainly used in pharmaceutical intermediates, agrochemical intermediates, fine chemicals, specialty chemicals, polymer synthesis, and various organic reactions requiring a strong base.
Q: 2. Why is Sodium tert-Butoxide preferred over some inorganic bases?
A: Its strong basicity and steric hindrance often provide better reaction selectivity, helping reduce unwanted side reactions and improve product purity.
Q: 3. Is Sodium tert-Butoxide suitable for pharmaceutical manufacturing?
A: Yes. It is widely used in the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients where reaction control and product quality are critical.
Q: 4. What documents can be provided?
A: We can provide COA, SDS, packing details, and other export-related documentation according to customer requirements.
Q: 5. How should Sodium tert-Butoxide be stored?
A: It should be stored in a tightly sealed container in a cool, dry environment away from moisture, air, and incompatible substances.
Q: 6. Can you support bulk international orders?
A: Yes. Xima Chemical has extensive experience supplying global customers and can arrange efficient export logistics and customized packaging solutions.
Q: 7. How can I request a quotation?
A: Simply send us your required quantity, destination port, application details, and packaging requirements. Our team will provide a prompt and competitive quotation.
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